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产品信息
PA5-72206
产品规格
种属反应
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 132-165 amino acids from the N-terminal region of DANRE sh3bp4a
偶联物
形式
Liquid
浓度
2.76 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718060
靶标信息
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SH3 domain-binding protein 4-A; SH3-domain binding protein 4; src homology 3 binding protein 4
基因别名: sh3bp4; sh3bp4a; si:dkey-110p14.1
UniProt ID: (Zebrafish) Q1LVQ2
Entrez Gene ID: (Zebrafish) 403082
