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产品信息
H00057619-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SHROOM3 (AAI56133.1, 1 a.a. approximately 1995 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRTTEDFHKP SATLNSNTAT KGRYIYLEAF LEGGAPWGFT LKGGLEHGEP LIISKVEEGG KADTLSSKLQ AGDEVVHINE VTLSSSRKEA VSLVKGSYKT LRLVVRRDVC TDPGHADTGA SNFVSPEHLT SGPQHRKAAW SGGVKLRLKH RRSEPAGRPH SWHTTKSGEK QPDASMMQIS QGMIGPPWHQ SYHSSSSTSD LSNYDHAYLR RSPDQCSSQG SMESLEPSGA YPPCHLSPAK STGSIDQLSH FHNKRDSAYS SFSTSSSILE YPHPGISGRE RSGSMDNTSA RGGLLEGMRQ ADIRYVKTVY DTRRGVSAEY EVNSSALLLQ GREARASANG QGYDKWSNIP RGKGVPPPSW SQQCPSSLET ATDNLPPKVG APLPPARSDS YAAFRHRERP SSWSSLDQKR LCRPQANSLG SLKSPFIEEQ LHTVLEKSPE NSPPVKPKHN YTQKAQPGQP LLPTSIYPVP SLEPHFAQVP QPSVSSNGML YPALAKESGY IAPQGACNKM ATIDENGNQN GSGRPGFAFC QPLEHDLLSP VEKKPEATAK YVPSKVHFCS VPENEEDASL KRHLTPPQGN SPHSNERKST HSNKPSSHPH SLKCPQAQAW QAGEDKRSSR LSEPWEGDFQ EDHNANLWRR LEREGLGQSL SGNFGKTKSA FSSLQNIPES LRRHSSLELG RGTQEGYPGG RPTCAVNTKA EDPGRKAAPD LGSHLDRQVS YPRPEGRTGA SASFNSTDPS PEEPPAPSHP HTSSLGRRGP GPGSASALQG FQYGKPHCSV LEKVSKFEQR EQGSQRPSVG GSGFGHNYRP HRTVSTSSTS GNDFEETKAH IRFSESAEPL GNGEQHFKNG ELKLEEASRQ PCGQQLSGGA SDSGRGPQRP DARLLRSQST FQLSSEPERE PEWRDRPGSP ESPLLDAPFS RAYRNSIKDA QSRVLGATSF RRRDLELGAP VASRSWRPRP SSAHVGLRSP EASASASPHT PRERHSVTPA EGDLARPVPP AARRGARRRL TPEQKKRSYS EPEKMNEVGI VEEAEPAPLG PQRNGMRFPE SSVADRRRLF ERDGKACSTL SLSGPELKQF QQSALADYIQ RKTGKRPTSA AGCSLQEPGP LRERAQSAYL QPGPAALEGS GLASASSLSS LREPSLQPRR EATLLPATVA ETQQAPRDRS SSFAGGRRLG ERRRGDLLSG ANGGTRGTQR GDETPREPSS WGARAGKSMS AEDLLERSDV LAGPVHVRSR SSPATADKRQ DVLLGQDSGF GLVKDPCYLA GPGSRSLSCS ERGQEEMLPL FHHLTPRWGG SGCKAIGDSS VPSECPGTLD HQRQASRTPC PRPPLAGTQG LVTDTRAAPL TPIGTPLPSA IPSGYCSQDG QTGRQPLPPY TPAMMHRSNG HTLTQPPGPR GCEGDGPEHG VEEGTRKRVS LPQWPPPSRA KWAHAAREDS LPEESSAPDF ANLKHYQKQQ SLPSLCSTSD PDTPLGAPST PGRISLRISE SVLRDSPPPH EDYEDEVFVR DPHPKATSSP TFEPLPPPPP PPPSQETPVY SMDDFPPPPP HTVCEAQLDS EDPEGPRPSF NKLSKVTIAR ERHMPGAAHV VGSQTLASRL QTSIKGSEAE STPPSFMSVH AQLAGSLGGQ PAPIQTQSLS HDPVSGTQGL EKKVSPDPQK SSEDIRTEAL AKEIVHQDKS LADILDPDSR LKTTMDLMEG LFPRDVNLLK ENSVKRKAIQ RTVSSSGCEG KRNEDKEAVS MLVNCPAYYS VSAPKAELLN KIKEMPAEVN EEEEQADVNE KKAELIGSLT HKLETLQEAK GSLLTDIKLN NALGEEVEAL ISELCKPNEF DKYRMFIGDL DKVVNLLLSL SGRLARVENV LSGLGEDASN EERSSLYEKR KILAGQHEDA RELKENLDRR ERVVLGILAN YLSEEQLQDY QHFVKMKSTL LIEQRKLDDK IKLGQEQVKC LLESLPSDFI PKAGALALPP NLTSEPIPAG GCTFSGIFPT LTSPL
靶标信息
SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium. SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: F-actin-binding; F-actin-binding protein; hShrmL; Protein Shroom3; Shroom-related protein
基因别名: APXL3; KIAA1481; MSTP013; SHRM; SHRML; SHROOM3
UniProt ID: (Human) Q8TF72
Entrez Gene ID: (Human) 57619
