Invitrogen

SIDT2 Polyclonal Antibody

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SIDT2 Antibody (PA5-69064) in WB

Western blot analysis of SIDT2 on human fetal brain tissue lysate. The sample was probed with a SIDT2 polyclonal antibody (Product # PA5-69064) using a primary antibody dilution of 1.0 µg/mL.

SIDT2 Antibody in Surface plasmon resonance (SPR)

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产品信息

PA5-69064

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.2-1.0 µg/mL

查看2篇已发表文章 2篇已发表文章

Surface plasmon resonance (SPR)

Assay-dependent

产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide directed towards the N terminal region of human SIDT2

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2688610

产品详细信息

This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

靶标信息

The SID1 transmembrane family member (SIDT2) is a highly glycosylated, multipass transmembrane protein that localizes to the lysosomal membrane. SIDT2 is highly expressed in liver, brain and kidney, with no or little expression in skeletal muscles, heart or other tissues. Little is known of the function of SIDT2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes.

Cells

Sampieri A,Asanov A,Méndez-Acevedo KM,Vaca L

PA5-69064 was used in Western Blot to provide evidence of a novel role for SIDT2 as a protein forming a complex with ApoA1 and enhancing its secretion to the extracellular space.

Tue Sep 26 00:00:00 UTC 2023

Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function.

Cell death & disease

Geng MY,Wang L,Song YY,Gu J,Hu X,Yuan C,Yang M,Pei WJ,Zhang Y,Gao JL

PA5-69064 was used in Western Blot to find that the kidneys of Sidt2-/- mice showed changes in basement membrane thickening, foot process fusion, and mitochondrial swelling.

Sat Dec 18 00:00:00 UTC 2021

Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function.

Cell death & disease

Geng MY,Wang L,Song YY,Gu J,Hu X,Yuan C,Yang M,Pei WJ,Zhang Y,Gao JL

PA5-69064 was used in Western Blot to find that the kidneys of Sidt2-/- mice showed changes in basement membrane thickening, foot process fusion, and mitochondrial swelling.