Product References
The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.
Inflammopharmacology
El-Maraghy SA,Reda A,Essam RM,Kortam MA
PA5-17074 was used in Western Blotting to provide a strong verification for the therapeutic influence of Nobiletin in AD.
Sun Oct 01 00:00:00 UTC 2023
The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.
Inflammopharmacology
El-Maraghy SA,Reda A,Essam RM,Kortam MA
PA5-17074 was used in Western Blotting to provide a strong verification for the therapeutic influence of Nobiletin in AD.
Sun Oct 01 00:00:00 UTC 2023
Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice.
EMBO molecular medicine
Farini A,Tripodi L,Villa C,Strati F,Facoetti A,Baselli G,Troisi J,Landolfi A,Lonati C,Molinaro D,Wintzinger M,Gatti S,Cassani B,Caprioli F,Facciotti F,Quattrocelli M,Torrente Y
PA5-17074 was used in Western Blotting to identify a potential role for the gut microbiota in the pathogenesis of DMD.
Wed Mar 08 00:00:00 UTC 2023
Vitamin D Prevents High Glucose-Induced Lipid Droplets Accumulation in Cultured Endothelial Cells: The Role of Thioredoxin Interacting Protein.
Biomedicines
Scrimieri R,Cazzaniga A,Castiglioni S,Maier JAM
PA5-17074 was used in Western Blot to highlight TXNIP as one of the targets of VitD in high glucose-cultured endothelial cells and shed some light on the protective effect of VitD on the endothelium.
Fri Dec 10 00:00:00 UTC 2021
Vitamin D Prevents High Glucose-Induced Lipid Droplets Accumulation in Cultured Endothelial Cells: The Role of Thioredoxin Interacting Protein.
Biomedicines
Scrimieri R,Cazzaniga A,Castiglioni S,Maier JAM
PA5-17074 was used in Western Blot to highlight TXNIP as one of the targets of VitD in high glucose-cultured endothelial cells and shed some light on the protective effect of VitD on the endothelium.
Fri Dec 10 00:00:00 UTC 2021
Acid Loading Unmasks Glucose Homeostatic Instability in Proximal-Tubule-Targeted Insulin/Insulin-Like-Growth-Factor-1 Receptor Dual Knockout Mice.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Aljaylani A,Fluitt M,Piselli A,Shepard BD,Tiwari S,Ecelbarger CM
PA5-17074 was used in Western Blotting to demonstrate an important role for insulin and/or IGF1 receptor signaling in the renal proximal tubule to reduce excursions in blood glucose.
Sat Jul 18 00:00:00 UTC 2020
MiR-132 regulates osteogenic differentiation via downregulating Sirtuin1 in a peroxisome proliferator-activated receptor β/δ-dependent manner.
Biochemical and biophysical research communications
Gong K,Qu B,Liao D,Liu D,Wang C,Zhou J,Pan X
PA5-17074 was used in western blot to elucidate mechanisms by which miR-132 regulates osteogenic differentiation
Fri Sep 09 00:00:00 UTC 2016
Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor γ in MC3T3-E1 cells.
Biochemical and biophysical research communications
Qu B,Ma Y,Yan M,Gong K,Liang F,Deng S,Jiang K,Ma Z,Pan X
PA5-17074 was used in immunoprecipitation and western blot to investigate the molecular mechanism of Sirt1 in osteogenic differentiation
Fri Sep 09 00:00:00 UTC 2016