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SIRT7 Antibody (PA5-13226) in IHC (P)
Immunohistochemistry analysis of SIRT7 in paraformaldehyde-fixed, paraffin-embedded human esophagus tissue sections. Samples were incubated with SIRT7 polyclonal antibody (Product # PA5-13226) using a dilution of 1:25 for 1 hours at 37°C followed by an undiluted biotinylated goat polyvalent antibody. Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5 hour at room temperature; antigen retriev... View More
产品信息
PA5-13226
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human SIRT7
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2188947
产品详细信息
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
靶标信息
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC126840; MGC126842; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein deacylase sirtuin-7; Regulatory protein SIR2 homolog 7; silent mating type information regulation 2, S.cerevisiae, homolog 7; SIR2-like protein 7; sir2-related protein type 7; sirtuin type 7
基因别名: SIR2L7; SIRT7
UniProt ID: (Human) Q9NRC8
Entrez Gene ID: (Human) 51547
