Rockland

SIX3 Polyclonal Antibody

查看其他13个SIX3抗体

产品信息

200-201-A26

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化 (IHC)

1:250-1:500

-

酶联免疫吸附实验 (ELISA)

1:5,000-1:25,000

-

产品规格

种属反应

Mouse

宿主/亚型

Guinea pig

分类

Polyclonal

类型

Antibody

抗原

This Protein A purified antibody was prepared from whole guinea pig serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse Six3 protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.65 mg/mL

纯化类型

Protein A

保存液

0.02M potassium phosphate, pH 7.2, with 0.15M NaCl

内含物

0.01% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

This antibody reacts with mouse Six3. Cross-reactivity with Six3 from other sources has not been determined.

靶标信息

This gene encodes a member of the sine oculis homeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in this gene have been associated with holoprosencephaly type 2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Homeobox protein SIX3; Sine oculis homeobox homolog 3; sine oculis-related homeobox 3 homolog

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基因别名: E130112M24Rik; Six3; Six3a; Six3alpha; Six3b; Six3beta

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UniProt ID: (Mouse) Q62233

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Entrez Gene ID: (Mouse) 20473

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RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding transcription corepressor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription coactivator activity receptor binding protein binding histone deacetylase binding sequence-specific DNA binding homeodomain transcription factor

protein import into nucleus, translocation eye development epithelial cell maturation lens development in camera-type eye optic vesicle morphogenesis transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter protein import into nucleus multicellular organism development brain development proximal/distal axis specification neuroblast differentiation diencephalon development telencephalon development forebrain anterior/posterior pattern specification forebrain dorsal/ventral pattern formation cell proliferation in forebrain telencephalon regionalization pituitary gland development negative regulation of Wnt signaling pathway regulation of cell proliferation camera-type eye development negative regulation of neuron differentiation negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter circadian behavior lens induction in camera-type eye regulation of neural retina development lens fiber cell differentiation neuroblast migration regulation of cell cycle phase transition regulation of neuroblast proliferation apoptotic process involved in development lens fiber cell apoptotic process regulation of neural precursor cell proliferation