Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
OSS00265W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from c-terminal region of human SLC12A2 conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: SLC12A2.
靶标信息
NKCC1 mediates sodium and chloride transport and reabsorption. NKCC1 is a membrane protein and is important in maintaining proper ionic balance and cell volume. NKCC1 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, NKCC1 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for NKCC1. Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Basolateral Na-K-Cl symporter; BSC2; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; hNKCC1; mNKCC1; Na-K-2Cl cotransporter 1; protein phosphatase 1, regulatory subunit 141; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; Solute carrier family 12 member 2; solute carrier family 12, member 2
基因别名: 9330166H04Rik; BSC; BSC2; mBSC2; NKCC1; PPP1R141; SLC12A2; sy-ns
UniProt ID: (Human) P55011, (Mouse) P55012
Entrez Gene ID: (Human) 6558, (Rat) 83629, (Mouse) 20496
transport
ion transport
potassium ion transport
sodium ion transport
ammonium transport
transepithelial chloride transport
transepithelial ammonium transport
ammonium transmembrane transport
chloride transmembrane transport
chloride transport
hyperosmotic response
gamma-aminobutyric acid signaling pathway
aging
multicellular organism growth
positive regulation of cell volume
detection of mechanical stimulus involved in sensory perception of sound
branching involved in mammary gland duct morphogenesis
mammary duct terminal end bud growth
organic cation transport
transmembrane transport
