Search Thermo Fisher Scientific
Immunogen sequence: AQALSVQDKG LGGLQPAQSP PLSPEDSLGA VGPASLEQRQ SDPYLAQAPA PQAAEFLSPV TTPSPCTLCS AQASGPEAAD ETCPQLAVHP PGVSKLGLQC LPSDGVQNV
Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 27%.
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cyclic dinucleotide:anion antiporter SLC19A1; Folate:anion antiporter SLC19A1; FOLT; hSLC19A1; IFC-1; Intestinal folate carrier 1; Placental folate transporter; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; RFC; RFT-1; solute carrier family 19 (folate transporter), member 1; Solute carrier family 19 member 1
基因别名: CHMD; FLOT1; FOLT; IFC1; REFC; RFC1; SLC19A1
UniProt ID: (Human) P41440
Entrez Gene ID: (Human) 6573