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SLC19A1 Antibody (PA5-88778) in WB
Western blot analysis of SLC19A1 in extracts of various cell lines. Samples were incubated with SLC19A1 Polyclonal antibody (Product # PA5-88778) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88778
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_9192311)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805125
产品详细信息
Immunogen sequence: LDGLRHCQRG HHPRQPPAQG LRSAAEEKAA QALSVQDKGL GGLQPAQSPP LSPEDSLGAV GPASLEQRQS DPYLAQAPAP QAAEFLSPVT TPSPCTLCSA QASGPEAADE TCPQLAVHPP GVSKLGLQCL PSDGVQNVNQ; Positive Samples: HeLa, U-87MG; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cyclic dinucleotide:anion antiporter SLC19A1; Folate:anion antiporter SLC19A1; FOLT; hSLC19A1; IFC-1; Intestinal folate carrier 1; Placental folate transporter; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; RFC; RFT-1; solute carrier family 19 (folate transporter), member 1; Solute carrier family 19 member 1
基因别名: CHMD; FLOT1; FOLT; IFC1; REFC; RFC1; SLC19A1
UniProt ID: (Human) P41440
Entrez Gene ID: (Human) 6573
