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SLC22A1 Antibody (ACT-011-200UL) in WB
Western blot analysis of rat small intestine lysate (lanes 1 and 3) and rat H4-II-E-C3 hepatoma cell lysate (lanes 2 and 4): - 1-2. Anti-SLC22A1 Antibody (#ACT-011), (1:200).3-4. Anti-SLC22A1 Antibody , preincubated with SLC22A1 Blocking Peptide (#BLP-CT011).
产品信息
ACT-011-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)ENLGRRKSKAKENT, corresponding to amino acid residues 530- 543 of rat OCT1, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; mOCT1; Organic cation transporter 1; rOCT1; Solute carrier family 22 member 1; solute carrier family 22, member 1; SYK
基因别名: Lx1; Oct1; Orct; Orct1; Roct1; Slc22a1
UniProt ID: (Rat) Q63089, (Mouse) O08966
Entrez Gene ID: (Rat) 24904, (Mouse) 20517
acetylcholine transmembrane transporter activity
dopamine transmembrane transporter activity
norepinephrine transmembrane transporter activity
monoamine transmembrane transporter activity
secondary active organic cation transmembrane transporter activity
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
identical protein binding
protein homodimerization activity
transporter activity
ion transmembrane transporter activity
transmembrane transporter activity
secondary carrier transporter
cation transport
neurotransmitter transport
drug transmembrane transport
establishment or maintenance of transmembrane electrochemical gradient
organic cation transport
quaternary ammonium group transport
monoamine transport
dopamine transport
norepinephrine transport
epinephrine transport
protein homooligomerization
ammonium transmembrane transport
cation transmembrane transport
acetate ester transport
transport
ion transport
ion transmembrane transport
transmembrane transport
