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产品信息
PA5-42043
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human SLC22A1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2610367
产品详细信息
Peptide sequence: IAIQMICLVN AELYPTFVSG VGPACRGSDA TSSRDQGGRF ARDHEGRREP
Sequence homology: Human: 100%
靶标信息
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
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生物信息学
蛋白别名: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; hOCT1; Organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; Solute carrier family 22 member 1; SYK
基因别名: HOCT1; OCT1; oct1_cds; SLC22A1
UniProt ID: (Human) O15245
Entrez Gene ID: (Human) 6580
acetylcholine transmembrane transporter activity
dopamine transmembrane transporter activity
norepinephrine transmembrane transporter activity
protein binding
secondary active organic cation transmembrane transporter activity
organic cation transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
protein homodimerization activity
secondary carrier transporter
neurotransmitter transport
drug transmembrane transport
establishment or maintenance of transmembrane electrochemical gradient
organic cation transport
quaternary ammonium group transport
dopamine transport
norepinephrine transport
epinephrine transport
protein homooligomerization
ammonium transmembrane transport
acetate ester transport
