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产品信息
PA5-18521
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (TTPDCRKKFWKN) corresponding to the internal amino acids of SLC24A5 (aa 321-332).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10983529
产品详细信息
This antibody is predicted to react with canine and human based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
靶标信息
The SLC24A5 gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ion transporter JSX; K-independent Na+/Ca2+ exchanger JSX; Na(+)/K(+)/Ca(2+)-exchange protein 5; Na-Ca exchanger 5; oculocutaneous albinism 6 (autosomal recessive); sodium/potassion/calcium exchanger 5; Sodium/potassium/calcium exchanger 5; solute carrier family 24 (sodium/potassium/calcium exchanger), member 5; Solute carrier family 24 member 5; solute carrier family 24, member 5
基因别名: F630045L20Rik; JSX; NCKX5; NCX5; OCA6; SHEP4; SLC24A5
UniProt ID: (Human) Q71RS6, (Mouse) Q8C261
Entrez Gene ID: (Human) 283652, (Mouse) 317750, (Rat) 311387
transport
ion transport
potassium ion transport
sodium ion transport
calcium ion transport
ion transmembrane transport
sodium ion transmembrane transport
regulation of melanin biosynthetic process
negative regulation of melanin biosynthetic process
response to stimulus
transmembrane transport
calcium ion transmembrane transport
potassium ion transmembrane transport
cellular calcium ion homeostasis
