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产品信息
OSS00325W-100UL
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from aa region 30-100 of human SLC25A6 conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC25A6, 5.
靶标信息
SLC25A5 and SLC25A6 are members of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this genes functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. SLC25A5 forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of SLC25A5 gene has been shown to induce apoptosis and inhibit tumor growth. SLC25A6 is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); Adenine nucleotide translocator 3; ADP,ATP carrier protein 2; ADP,ATP carrier protein 3; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein, isoform T2; ADP,ATP carrier protein, liver; ADP/ATP translocase 2; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 2; ANT 3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; Solute carrier family 25 member 5; Solute carrier family 25 member 6
基因别名: 2F1; AAC2; AAC3; ANT; ANT 2; ANT 3; ANT2; ANT3; ANT3Y; CDABP0051; SLC25A5; SLC25A6; T2; T3
UniProt ID: (Human) P05141, (Human) P12236
Entrez Gene ID: (Human) 292, (Human) 293
translation
transport
chromosome segregation
positive regulation of cell proliferation
adenine transport
viral process
regulation of insulin secretion
transmembrane transport
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
protein targeting to mitochondrion
apoptotic process
ADP transport
ATP transport
active induction of host immune response by virus
