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Sequence of this protein is as follows: MSSESKEQHN VSPRDSAEGN DSYPSGIHLE LQRESSTDFK QFETNDQCRP YHRILIERQE KSDTNFKEFV IKKLQKNCQC SPAKAKNMIL GFLPVLQWLP KYDLKKNILG DVMSGLIVGI LLVPQSIAYS LLAGQEPVYG LYTSFFASII YFLLGTSRHI SVGIFGVLCL MIGETVDREL QKAGYDNAHS APSLGMVSNG STLLNHTSDR ICDKSCYAIM VGSTVTFIAG VYQVAMGFFQ VGFVSVYLSD ALLSGFVTGA SFTILTSQAK YLLGLNLPRT NGVGSLITTW IHVFRNIHKT NLCDLITSLL CLLVLLPTKE LNEHFKSKLK APIPIELVVV VAATLASHFG KLHENYNSSI AGHIPTGFMP PKVPEWNLIP SVAVDAIAIS IIGFAITVSL SEMFAKKHGY TVKANQEMYA IGFCNIIPSF FHCFTTSAAL AKTLVKESTG CHTQLSGVVT ALVLLLVLLV IAPLFYSLQK SVLGVITIVN LRGALRKFRD LPKMWSISRM DTVIWFVTML SSALLSTEIG LLVGVCFSIF CVILRTQKPK SSLLGLVEES EVFESVSAYK NLQTKPGIKI FRFVAPLYYI NKECFKSALY KQTVNPILIK VAWKKAAKRK IKEKVVTLGG IQDEMSVQLS HDPLELHTIV IDCSAIQFLD TAGIHTLKEV RRDYEAIGIQ VLLAQCNPTV RDSLTNGEYC KKEEENLLFY SVYEAMAFAE VSKNQKGVCV PNGLSLSSD
The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Diastrophic dysplasia protein; solute carrier family 26 (anion exchanger), member 2; solute carrier family 26 (sulfate transporter), member 2; Solute carrier family 26 member 2; sulfate anion transporter 1; Sulfate transporter
基因别名: D5S1708; DTD; DTDST; EDM4; MST153; MSTP157; SLC26A2
UniProt ID: (Human) P50443
Entrez Gene ID: (Human) 1836