Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
SLC26A2 Antibody (PA5-110385) in WB
Western blot analysis of SLC26A2 in extracts of various cell lines. Samples were incubated with SLC26A2 Polyclonal antibody (Product # PA5-110385) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-110385
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human SLC26A2 (NP_000103.2).
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855796
产品详细信息
Immunogen sequence: MSSESKEQHN VSPRDSAEGN DSYPSGIHLE LQRESSTDFK QFETNDQCRP YHRILIERQE KSDTNFKEFV IKKLQKNCQC SPAKAKNMIL GFLPVLQWLP KYDLKKNILG D
靶标信息
The SLC26 family is comprised of sulfate/anion transporters that are well conserved in both their genomic and protein structures, yet have markedly different tissue expression patterns. Members of the SLC26 family can mediate the electroneutral exchange of Cl- for HCO3- across the plasma membrane of mammalian cells. SLC26A2 (solute carrier family 26, member 2), also known as DTD, EDM4, DTDST, MST153, D5S1708 or MSTP157, is a 739 amino acid diastrophic dysplasia sulfate transporter belonging to the SLC26A/SulP transporter family. Ubiquitously expressed, SLC26A2 may play a role in endochondral bone formation. SLC26A2 is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias and is critical for sulfation of proteoglycans and matrix organization in cartilage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Diastrophic dysplasia protein; Diastrophic dysplasia protein homolog; solute carrier family 26 (anion exchanger), member 2; solute carrier family 26 (sulfate transporter), member 2; Solute carrier family 26 member 2; ST-OB; sulfate anion transporter 1; Sulfate transporter
基因别名: D5S1708; DTD; DTDST; EDM4; MST153; MSTP157; SLC26A2; ST-OB
UniProt ID: (Human) P50443, (Mouse) Q62273, (Rat) O70531
Entrez Gene ID: (Human) 1836, (Mouse) 13521, (Rat) 117267
ossification
ion transport
sulfate transport
bicarbonate transport
oxalate transport
regulation of membrane potential
3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
regulation of intracellular pH
sulfate transmembrane transport
chloride transmembrane transport
transport
transmembrane transport
