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SLC26A4 Antibody (PA5-115911) in ICC/IF
Immunocytochemistry analysis of SLC26A4 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115911) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
产品信息
PA5-115911
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SLC26A4(Accession O43511), corresponding to amino acid residues L498-L548.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900545
产品详细信息
Antibody detects endogenous levels of total SLC26A4.
靶标信息
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Pendred syndrome homolog; Pendred's syndrome; Pendrin; Sodium-independent chloride/iodide transporter; solute carrier family 26 (anion exchanger), member 4; Solute carrier family 26 member 4; solute carrier family 26, member 4; truncated solute carrier family 26
基因别名: DFNB4; EVA; PDS; pendrin; SLC26A4; TDH2B
UniProt ID: (Human) O43511, (Rat) Q9R154, (Mouse) Q9R155
Entrez Gene ID: (Human) 5172, (Rat) 29440, (Mouse) 23985
chloride channel activity
secondary active sulfate transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
iodide transmembrane transporter activity
sulfate transmembrane transporter activity
anion:anion antiporter activity
oxalate transmembrane transporter activity
anion transmembrane transporter activity
transporter
ion transport
regulation of pH
sensory perception of sound
sulfate transport
inorganic anion transport
bicarbonate transport
iodide transport
oxalate transport
regulation of protein localization
regulation of membrane potential
regulation of intracellular pH
sulfate transmembrane transport
chloride transmembrane transport
chloride transport
transport
organ morphogenesis
transmembrane transport
anion transmembrane transport
