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SLC27A1 Antibody (H00376497-D01P) in WB
Western Blot analysis of SLC27A1 expression in transfected 293T cell line (H00376497-T02) by SLC27A1 MaxPab polyclonal antibody.
Lane 1: SLC27A1 transfected lysate(71.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: SLC27A1 transfected lysate(71.10 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00376497-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SLC27A1 (NP_940982.1, 1 a.a. approximately 646 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MRAPGAGAAS VVSLALLWLL GLPWTWSAAA ALGVYVGSGG WRFLRIVCKT ARRDLFGLSV LIRVRLELRR HQRAGHTIPR IFQAVVQRQP ERLALVDAGT GECWTFAQLD AYSNAVANLF RQLGFAPGDV VAIFLEGRPE FVGLWLGLAK AGMEAALLNV NLRREPLAFC LGTSGAKALI FGGEMVAAVA EVSGHLGKSL IKFCSGDLGP EGILPDTHLL DPLLKEASTA PLAQIPSKGM DDRLFYIYTS GTTGLPKAAI VVHSRYYRMA AFGHHAYRMQ AADVLYDCLP LYHSAGNIIG VGQCLIYGLT VVLRKKFSAS RFWDDCIKYN CTVVQYIGEI CRYLLKQPVR EAERRHRVRL AVGNGLRPAI WEEFTERFGV RQIGEFYGAT ECNCSIANMD GKVGSCGFNS RILPHVYPIR LVKVNEDTME LLRDAQGLCI PCQAGEPGLL VGQINQQDPL RRFDGYVSES ATSKKIAHSV FSKGDSAYLS GDVLVMDELG YMYFRDRSGD TFRWRGENVS TTEVEGVLSR LLGQTDVAVY GVAVPGVEGK AGMAAVADPH SLLDPNAIYQ ELQKVLAPYA RPIFLRLLPQ VDTTGTFKIQ KTRLQREGFD PRQTSDRLFF LDLKQGHYLP LNEAVYTRIC SGAFAL
靶标信息
SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACSVL5FATP-1; Arachidonate--CoA ligase; EC 6.2.1; FATP-1; Fatty acid transport protein; Fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; Long-chain-fatty-acid--CoA ligase; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; Solute carrier family 27 member 1; Very long-chain acyl-CoA synthetase; Vlc27a1
基因别名: ACSVL5; FATP; FATP-1; FATP1; SLC27A1
UniProt ID: (Human) Q6PCB7, (Mouse) Q60714
Entrez Gene ID: (Human) 376497, (Mouse) 26457
nucleotide binding
long-chain fatty acid-CoA ligase activity
fatty acid transporter activity
very long-chain fatty acid-CoA ligase activity
protein homodimerization activity
catalytic activity
acyl-CoA ligase activity
succinate-CoA ligase activity
3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity
fatty acid ligase activity
ligase activity
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
benzoyl acetate-CoA ligase activity
2,4-dichlorobenzoate-CoA ligase activity
pivalate-CoA ligase activity
cyclopropanecarboxylate-CoA ligase activity
adipate-CoA ligase activity
citronellyl-CoA ligase activity
mentha-1,3-dione-CoA ligase activity
thiophene-2-carboxylate-CoA ligase activity
2,4,4-trimethylpentanoate-CoA ligase activity
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
branched-chain acyl-CoA synthetase (ADP-forming) activity
aryl-CoA synthetase (ADP-forming) activity
3-hydroxypropionyl-CoA synthetase activity
perillic acid:CoA ligase (ADP-forming) activity
perillic acid:CoA ligase (AMP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity
pristanate-CoA ligase activity
malonyl-CoA synthetase activity
transporter
secondary carrier transporter
medium-chain fatty acid transport
long-chain fatty acid metabolic process
phosphatidylethanolamine biosynthetic process
phosphatidic acid biosynthetic process
phosphatidylglycerol biosynthetic process
phosphatidylcholine biosynthetic process
phosphatidylserine biosynthetic process
phosphatidylinositol biosynthetic process
response to cold
long-chain fatty acid transport
positive regulation of heat generation
cardiolipin biosynthetic process
response to insulin
adiponectin-activated signaling pathway
negative regulation of phospholipid biosynthetic process
positive regulation of protein serine/threonine kinase activity
lipid metabolic process
fatty acid metabolic process
transport
lipid transport
metabolic process
fatty acid transport
