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产品信息
PA5-36941
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 417-462 of human SLC28A2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553827
产品详细信息
This antibody detects endogenous protein at a molecular weight of 72 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CNT 2; CNT-2; Concentrative nucleoside transporter 2; Na(+)/nucleoside cotransporter 2; purine-selective Na+ nucleoside cotransporter; rCNT2; Sodium-coupled nucleoside transporter 2; Sodium/nucleoside cotransporter 2; Sodium/purine nucleoside co-transporter; Sodium/purine nucleoside cotransporter; solute carrier family 28 (concentrative nucleoside transporter), member 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; Solute carrier family 28 member 2; solute carrier family 28, member 2; SPNT
基因别名: 2010208B10Rik; B430217P18; BB152493; CNT2; HCNT2; HsT17153; SLC28A2; Spnt; SPNT1
UniProt ID: (Human) O43868, (Mouse) O88627, (Rat) Q62773
Entrez Gene ID: (Human) 9153, (Mouse) 269346, (Rat) 60423
