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SLC39A7 Antibody (PA5-21072) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human brain tissue using SLC39A7 Polyclonal Antibody (Product # PA5-21072) at 2.5 µg/mL. Tissue was fixed with formaldehyde and blocked with 0.1 serum for 1 h at RT; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody overnight at 4˚C. A goat anti-rabbit IgG H&L (HRP) at 1/250 was used as secondar... View More
产品信息
PA5-21072
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 17 amino acid peptide near the amino terminus of human ZIP7.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11157028
产品详细信息
A suggested positive control is mouse brain tissue lysate.
PA5-21072 can be used with blocking peptide PEP-1186.
靶标信息
The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DADB-100D22.3; H2-K region expressed gene 4; Histidine-rich membrane protein; Histidine-rich membrane protein Ke4; HLA class II region expressed gene KE4; Ke4 gene; Ke4 gene, mouse, human homolog of; Really interesting new gene 5 protein; RT1 class I, locus Ke4; RT1 region expressed gene KE4; solute carrier family 39 (zinc transporter), member 7; Solute carrier family 39 member 7; Zinc transporter SLC39A7; ZIP7; Zrt-, Irt-like protein 7
基因别名: AA408174; AI117660; AL024048; D6S115E; D6S2244E; H-2Ke4; H2-KE4; HKE4; Ke-4; KE4; RING5; RT1-Ke4; Rt1Ke4; SLC39A7; ZIP7
UniProt ID: (Human) Q92504, (Mouse) Q31125
Entrez Gene ID: (Human) 7922, (Mouse) 14977, (Rat) 294281
