Invitrogen

SLC4A8/SLC4A10 Polyclonal Antibody

SLC4A8/SLC4A10 Antibody in Immunocytochemistry (ICC/IF)

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SLC4A8/SLC4A10 Antibody (PA5-101904) in ICC/IF

Immunocytochemistry analysis of SLC4A8/SLC4A10 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SLC4A8/SLC4A10 polyclonal antibody (Product # PA5-101904) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 co... View More

SLC4A8/SLC4A10 Antibody in Western Blot (WB)

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产品信息

PA5-101904

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human SLC4A8(Accession Q2Y0W8), corresponding to amino acid residues F1040-S1090.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2851336

产品详细信息

Antibody detects endogenous levels of total SLC4A8/10.

靶标信息

This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Electroneutral Na(+)-driven Cl-HCO3 exchanger; Electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; k-NBC3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; slc4a8; slc4a8 {ECO:0000312|RGD:735164}; sodium bicarbonate cotransporter isoform 3 kNBC-3; sodium bicarbonate cotransporter member 10 variant NBCn2-E'; sodium bicarbonate cotransporter NBCn2-E; Sodium-driven chloride bicarbonate exchanger; solute carrier family 4 (anion exchanger), member 8; Solute carrier family 4 member 10; Solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8; solute carrier family 4, sodium bicarbonate cotransporter-like, member 10; solute carrier family 4, sodium bicarbonate transporter, member 10; solute carrier family 4, sodium bicarbonate transporter-like, member 10

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基因别名: AW493845; C230026C11; KIAA0739; Kiaa4136; kNBC-3; mKIAA4136; NBC; NBC3; NBCN2; NCBE; NDCBE; NDCBE1; SLC4A10; SLC4A8