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SLC7A2 Antibody (PA5-89910) in IHC (P)
Immunohistochemistry analysis of SLC7A2 in paraffin-embedded human mammary cancer. Samples were incubated with SLC7A2 Polyclonal antibody (Product # PA5-89910) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-89910
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 559-658 of human SLC7A2 (NP_0010085393)
偶联物
形式
Liquid
浓度
1.56 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805837
产品详细信息
Immunogen sequence: PRNLSSPFIF HEKTSEF
Positive Samples: 293T, HepG2, HeLa, Mouse liver, Mouse brain, Rat liver; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 20.5; amino acid transporter, cationic 2 (low affinity); CAT-2; Cationic amino acid transporter 2; cationic amino acid transporter 2A; cationic amino acid transporter 2B; cationic amino acid transporter-2A; Low affinity cationic amino acid transporter 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; Solute carrier family 7 member 2; solute carrier family 7, member 2; T-cell early activation protein; TEA
基因别名: 20.5; AI158848; ATRC2; CAT-2; CAT2; Cat2a; Cat2b; HCAT2; SLC7A2; Tea
UniProt ID: (Human) P52569, (Mouse) P18581, (Rat) B5D5N9
Entrez Gene ID: (Human) 6542, (Mouse) 11988, (Rat) 64554
high-affinity arginine transmembrane transporter activity
high-affinity lysine transmembrane transporter activity
amino acid transmembrane transporter activity
basic amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
antiporter activity
low-affinity L-arginine transmembrane transporter activity
high-affinity L-ornithine transmembrane transporter activity
L-ornithine transmembrane transporter activity
arginine transmembrane transporter activity
L-lysine transmembrane transporter activity
L-arginine transmembrane transporter activity
amino acid transporter
nitric oxide production involved in inflammatory response
cellular amino acid metabolic process
nitric oxide biosynthetic process
transport
amino acid transport
L-amino acid transport
arginine transport
macrophage activation
regulation of macrophage activation
regulation of inflammatory response
L-arginine import across plasma membrane
L-lysine import across plasma membrane
L-ornithine import across plasma membrane
basic amino acid transmembrane transport
amino acid transmembrane transport
transmembrane transport
L-arginine transport
L-ornithine transmembrane transport
L-arginine transmembrane transport
arginine transmembrane transport
cation transmembrane transport
L-alpha-amino acid transmembrane transport
