Invitrogen

SLC8B1 Polyclonal Antibody

SLC8B1 Antibody in Immunocytochemistry (ICC/IF)

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SLC8B1 Antibody (PA5-114330) in ICC/IF

Immunocytochemical analysis of SLC8B1 in SKOV-3 cells using a SLC8B1 polyclonal antibody (Product #PA5-114330). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with the primary antibody for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 Goat anti-Rabbit IgG was used as the secondary antibody at 1:100 dilution. The nuclear counter stain is DAPI.

SLC8B1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

SLC8B1 Antibody in Flow Cytometry (Flow)

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产品信息

PA5-114330

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

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免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:50-1:100

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein within Human SLC8B1 aa 229-406

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2890499

靶标信息

SLC24A6 belongs to a family of potassium-dependent sodium/calcium exchangers that maintain cellular calcium homeostasis through the electrogenic counter transport of 4 sodium ions for 1 calcium ion and 1 potassium ion.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic.

The Journal of biological chemistry

Hagenston AM,Yan J,Bas-Orth C,Tan Y,Sekler I,Bading H

PA5-114330 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to investigate NCLX expression effects on mitochondria in neurones.

Tue Feb 01 00:00:00 UTC 2022

生物信息学

蛋白别名: Mitochondrial sodium/calcium exchanger protein; Na(+)/K(+)/Ca(2+)-exchange protein 6; Sodium/calcium exchanger protein, mitochondrial; Sodium/potassium/calcium exchanger 6; sodium/potassium/calcium exchanger 6, mitochondrial; solute carrier family 24 (sodium/lithium/calcium exchanger), member 6; solute carrier family 24 (sodium/potassium/calcium exchanger), member 6; Solute carrier family 24 member 6; solute carrier family 8 (sodium/lithium/calcium exchanger), member B1; Solute carrier family 8 member B1

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基因别名: AF261233; NCKX6; NCLX; SLC24A6; SLC8B1

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UniProt ID: (Human) Q6J4K2, (Mouse) Q925Q3, (Rat) Q6AXS0

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Entrez Gene ID: (Human) 80024, (Mouse) 170756, (Rat) 498185

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功能

calcium:sodium antiporter activity calcium:cation antiporter activity protein homodimerization activity calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential antiporter activity identical protein binding primary active transporter

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