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SLCO4C1 Antibody (PA5-112274) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SLCO4C1 in U251MG cells. Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with SLCO4C1 Polyclonal Antibody (Product # PA5-112274) (1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
产品信息
PA5-112274
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human SLCO4C1 fragment
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2867010
靶标信息
Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion- transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OATP-H; OATP-M1; OATP4C1; Organic anion transporter M1; Organic anion transporting polypeptide 4C1; SLCO4C1; Solute carrier family 21 member 20; Solute carrier organic anion transporter family member 4C1; solute carrier organic anion transporter family, member 4C1
基因别名: OATP-H; OATP-M1; OATP4C1; OATPX; PRO2176; SLC21A20; SLCO4C1
UniProt ID: (Human) Q6ZQN7
Entrez Gene ID: (Human) 353189
