Invitrogen

SLITRK6 Polyclonal Antibody

SLITRK6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SLITRK6 Antibody (PA5-33055) in IHC (P)

Immunohistochemistry analysis of SLITRK6 in human prostate. Samples were incubated with SLITRK6 polyclonal antibody (Product # PA5-33055). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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产品信息

PA5-33055

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

15 µg/mL

产品规格

种属反应

Hamster, Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 16 amino acid peptide from internal region of human SLITRK6.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2550516

产品详细信息

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Rat, Hamster (100%); Gorilla, Galago, Marmoset, Mouse, Elephant, Pig (94%); Panda, Bovine, Bat, Dog, Horse, Zebra finch, Chicken (88%); Opossum, Turkey (81%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

靶标信息

SLIT and NTRK-like family 6 (Slitrk6) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Slitrk6 expression has been observed in tissues such as tongue, lung, gastrointestinal tract, and pancreas. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk6 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. At least two isoforms of Slitrk6 are known to exisit.

仅用于科研。不用于诊断过程。未经明确授权不得转售。