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Product Details
PA5-51708
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLMAP. Recombinant protein control fragment (Product #RP-102135).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2647594
Product Specific Information
Immunogen sequence: SEYEKEITSL QNSFQLRCQQ CEDQQREEAT RLQGELEKLR KEWNALETEC HSLKRENVLL SSELQRQEKE LHNSQKQSLE LTSDLSILQM SRKELENQVG SLKEQHLRDS ADLKTLLSKA ENQAKDVQKE YEKTQTVLSE LKLKFEMTEQ
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.
Target Information
Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sarcolemmal membrane-associated protein; Sarcolemmal-associated protein
Gene Aliases: KIAA1601; SLAP; SLMAP; UNQ1847/PRO3577
UniProt ID: (Human) Q14BN4
Entrez Gene ID: (Human) 7871, (Rat) 290533
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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