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Product Details
PA5-96610
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1756-2005 of human SMCHD1 (NP_0561102)
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808412
Product Specific Information
Immunogen sequence: TTDAARRIYD ETQGRQQVLP LDSIYKKTLP DWKRSLPHFR NGKLYFKPIG DPVFARDLLT FPDNVEHCET VFGMLLGDTI ILDNLDAANH YRKEVVKITH CPTLLTRDGD RIRSNGKFGG LQNKAPPMDK LRGMVFGAPV PKQCLILGEQ IDLLQQYRSA VCKLDSVNKD LNSQLEYLRT PDMRKKKQEL DEHEKNLKLI EEKLGMTPIR KCNDSLRHSP KVETTDCPVP PKRMRREATR QNRIITKTDV; Positive Samples: HL-60, SKOV3, Jurkat, U-251MG, HepG2, Rat brain; Cellular Location: Chromosome
Target Information
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain containing 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
Gene Aliases: KIAA0650; RGD1307234; SMCHD1
UniProt ID: (Human) Q9H6Q2
Entrez Gene ID: (Human) 23347, (Rat) 316732
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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