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SMCHD1 Antibody (MA5-24709) in ICC/IF
Immunofluorecent analysis of SMCHD1 in U-2 OS cells using SMCHD1 Monoclonal Antibody (CL4270) (Product # MA5-24709). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
产品信息
MA5-24709
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
CL4270
抗原
Recombinant Human SMCHD1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2661949
产品详细信息
Immunogen sequence: DNGRGMTSKQL NNWAVYRLSK FTRQGDFESD HSGYVRPVPV PRSLNSDISY FGVGGKQAVF FVGQSARMIS KPADSQDVHE LVLSKED
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 98%.
靶标信息
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SMC hinge domain-containing protein 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
基因别名: KIAA0650; SMCHD1
UniProt ID: (Human) Q9H6Q2
Entrez Gene ID: (Human) 23347
