Invitrogen

SMOC1 Polyclonal Antibody

SMOC1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SMOC1 Antibody (PA5-31392) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using SMOC1 (Product # PA5-31392) antibody at 1:250 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

SMOC1 Antibody in Immunocytochemistry (ICC/IF)

SMOC1 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

SMOC1 Antibody — Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. Loss of signal was observed for target protein in culture media from SMOC1 knockout (KO) cells using Anti-SMOC1 polyclonal antibody (Product # PA5-31392). Ponceau stained transfer shown below. Data courtesy of YCharOS Inc., an open science company with the mission of characterizing commercially available antibodies using knockout validation. {KO}

产品信息

PA5-31392

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:100-1:1,000

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免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 140 and 363 of Human SMOC1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol, 1% BSA

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548866

产品详细信息

Recommended positive controls: U87-MG.

Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (84%), Bovine (95%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Pathogenetic Mechanisms Underlying Spinocerebellar Ataxia Type 3 Are Altered in Primary Oligodendrocyte Culture.

Cells

Schuster KH,Putka AF,McLoughlin HS

PA5-31392 was used in Immunocytochemistry to demonstrate that cell-autonomous dysfunction of oligodendrocyte maturation is one of the of the earliest and most robust changes in vulnerable regions of the SCA3 mouse brain.