Fabgennix

SMOX Polyclonal Antibody

查看其他10个SMOX抗体

产品信息

SMOX-101AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

酶联免疫吸附实验 (ELISA)

1:10,000

-

免疫沉淀 (IP)

1:50-1:250

-

产品规格

种属反应

Fruit fly

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide taken within amino acid region 434-484 on D. melanogaster SMOX protein.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1.5 mg/mL

纯化类型

Affinity chromatography

保存液

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CG2262-PA; CG2262-PB; LD15813p; R-Smad; sisters against dpp; Smox-PA; Smox-PB; Smox/dSmad2; temporarily deranged

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基因别名: CG2262; Dmel\CG2262; Dmel_CG2262; DSMAD2; l(1)G0348; Sad; Smad; SMAD2; SMOX; ted; tmp

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Entrez Gene ID: (Fruit fly) 31738

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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding chromatin DNA binding ubiquitin protein ligase binding I-SMAD binding DNA-binding transcription factor gene-specific transcriptional regulator

negative regulation of transcription from RNA polymerase II promoter positive regulation of neuroblast proliferation transforming growth factor beta receptor signaling pathway axon guidance imaginal disc-derived wing morphogenesis determination of adult lifespan anatomical structure morphogenesis negative regulation of autophagy mushroom body development cell differentiation BMP signaling pathway activin receptor signaling pathway glucose homeostasis regulation of imaginal disc-derived wing size R8 cell fate specification positive regulation of imaginal disc growth positive regulation of transcription from RNA polymerase II promoter neuron development dendrite morphogenesis regulation of synapse structure or activity SMAD protein signal transduction cellular response to glucose stimulus regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis