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产品信息
OSV00023W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the internal region of human SNF8 conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in rat, mouse and xenopus.
Specificity of this antibody: SNF8.
靶标信息
ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EAP30 subunit of ELL complex; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; hVps22; SNF8, ESCRT-II complex subunit, homolog; Vacuolar-sorting protein SNF8
基因别名: D11Moh34; Dot3; EAP30; RGD1310144; SNF8; VPS22
UniProt ID: (Human) Q96H20, (Mouse) Q9CZ28, (Rat) Q5RK19
Entrez Gene ID: (Human) 11267, (Mouse) 27681, (Rat) 287645
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transport
positive regulation of gene expression
regulation of multivesicular body size involved in endosome transport
protein transport
endocytic recycling
regulation of protein catabolic process
protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
early endosome to late endosome transport
positive regulation of protein catabolic process
regulation of protein complex stability
positive regulation of exosomal secretion
regulation of viral budding via host ESCRT complex
autophagy
endosomal transport
multivesicular body assembly
regulation of MAP kinase activity
multivesicular body sorting pathway
biological_process
