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SNRPB Antibody (PA5-110407) in IHC (P)
Immunohistochemistry analysis of SNRPB in paraffin-embedded human colon carcinoma. Samples were incubated with SNRPB Polyclonal antibody (Product # PA5-110407) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-110407
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPB (NP_003082.1).
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855818
Product Specific Information
Immunogen sequence: MTVGKSSKML QHIDYRMRCI LQDGRIFIGT FKAFDKHMNL ILCDCDEFRK IKPKNSKQAE REEKRVLGLV LLRGENLVSM TVEGPPPKDT GIARVPLAGA
Target Information
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B polypeptide of Sm protein; Sm protein B; Sm protein B/B'; Sm-B; Sm-B/B'; sm-B/Sm-B'; SM11; small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; Small nuclear ribonucleoprotein-associated protein B; Small nuclear ribonucleoprotein-associated proteins B and B'; smB; snRNP-B
Gene Aliases: AL024368; AU018828; CCMS; COD; SM-B; Sm-B/B'; SM11; SMB; SmB/B'; SmB/SmB'; SNRNP-B; SNRPB; SNRPB1
UniProt ID: (Human) P14678, (Mouse) P27048, (Rat) P17136
Entrez Gene ID: (Human) 6628, (Mouse) 20638, (Rat) 171365
spliceosomal snRNP assembly
mRNA splicing, via spliceosome
positive regulation of defense response to virus by host
termination of RNA polymerase II transcription
protein methylation
histone mRNA metabolic process
RNA splicing
nuclear import
mitophagy in response to mitochondrial depolarization
xenophagy
mRNA processing
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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