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Immunogen sequence: ILRFYTAQDG TDWLRAVSAN IRELTLQNMK MANKCCSPSD QVVHMGWVNE KLQGADSSQT FRPKFLALK
Syntrophin gamma 2 encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G2SYN; Gamma-2-syntrophin; gamma2-syntrophin; MGC133174; SYN5; syntrophin; syntrophin 5; syntrophin, gamma 2; Syntrophin-5
基因别名: G2SYN; SNTG2; SYN5
UniProt ID: (Human) Q9NY99
Entrez Gene ID: (Human) 54221