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产品信息
PA5-20308
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 16 amino acid peptide from near the carboxy terminus of human SkiP.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11154004
产品详细信息
A suggested positive control is mouse skeletal muscle tissue lysate.
PA5-20308 can be used with blocking peptide PEP-0402.
靶标信息
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homolog of Drosophila BX42; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; PPS; SKI interacting protein; SKI-interacting protein; SNW domain-containing protein 1
基因别名: 2310008B08Rik; AW048543; Bx42; NCOA-62; Prp45; PRPF45; RGD1561926; SKIIP; SKIP; SNW1
UniProt ID: (Human) Q13573, (Mouse) Q9CSN1
Entrez Gene ID: (Human) 22938, (Mouse) 66354, (Rat) 500695
negative regulation of transcription from RNA polymerase II promoter
mRNA splicing, via spliceosome
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA splicing
positive regulation of transforming growth factor beta receptor signaling pathway
skeletal muscle cell differentiation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation by host of viral transcription
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of mRNA splicing, via spliceosome
retinoic acid receptor signaling pathway
regulation of retinoic acid receptor signaling pathway
positive regulation of neurogenesis
positive regulation of histone H3-K4 methylation
regulation of vitamin D receptor signaling pathway
positive regulation of vitamin D receptor signaling pathway
cellular response to retinoic acid
biological_process
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
Notch signaling pathway
viral process
