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产品信息
PA5-27896
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 260 and 574 of Human SNX9
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545372
产品详细信息
Recommended positive controls: H1299, HCT116.
Predicted reactivity: Mouse (95%), Rat (94%), Xenopus laevis (84%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MST155; MSTP155; OTTHUMP00000040083; Protein SDP1; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Sorting nexin-9; Wiskott-Aldrich syndrome protein (WASP) interactor protein
基因别名: SDP1; SH3PX1; SH3PXD3A; SNX9; WISP
UniProt ID: (Human) Q9Y5X1
Entrez Gene ID: (Human) 51429
mitotic cytokinesis
intracellular protein transport
endocytosis
receptor-mediated endocytosis
mitotic nuclear division
vesicle organization
endosomal transport
positive regulation of protein oligomerization
cleavage furrow formation
positive regulation of GTPase activity
positive regulation of protein kinase activity
positive regulation of membrane protein ectodomain proteolysis
lipid tube assembly
membrane tubulation
cell-cell adhesion
