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Invitrogen
SOCS4 Polyclonal Antibody
Product Details
PA5-21599
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 376 and 440 of SOCS4 (Uniprot ID#Q8WXH5)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 40% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11152711
Product Specific Information
Recommended positive controls: HeLaS3.
Predicted reactivity: Pig (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: SH2 domain containing SOCS box protein; SOCS-4; SOCS-7; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7
Gene Aliases: SOCS4; SOCS7
UniProt ID: (Human) Q8WXH5
Entrez Gene ID: (Human) 122809
negative regulation of epidermal growth factor-activated receptor activity
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
regulation of growth
negative regulation of JAK-STAT cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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