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产品信息
PA5-21599
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 376 and 440 of SOCS4 (Uniprot ID#Q8WXH5)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 40% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152711
产品详细信息
Recommended positive controls: HeLaS3.
Predicted reactivity: Pig (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: SH2 domain containing SOCS box protein; SOCS-4; SOCS-7; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7
基因别名: SOCS4; SOCS7
UniProt ID: (Human) Q8WXH5
Entrez Gene ID: (Human) 122809
negative regulation of epidermal growth factor-activated receptor activity
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
regulation of growth
negative regulation of JAK-STAT cascade
