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产品信息
PA5-76324
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein of human SOCS4.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720051
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SH2 domain containing SOCS box protein; SOCS-4; SOCS-7; Suppressor of cytokine signaling 4; Suppressor of cytokine signaling 7; suppressor of cytokine signalling 4
基因别名: 3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; SOCS4; SOCS7
UniProt ID: (Human) Q8WXH5, (Mouse) Q91ZA6
Entrez Gene ID: (Human) 122809, (Mouse) 67296
negative regulation of epidermal growth factor-activated receptor activity
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
intracellular signal transduction
regulation of growth
negative regulation of JAK-STAT cascade
negative regulation of protein kinase activity
negative regulation of signal transduction
negative regulation of epidermal growth factor receptor signaling pathway
