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SON Antibody (PA5-95740) in WB
Western blot analysis of SON in extracts of various cell lines. Samples were incubated with SON Polyclonal antibody (Product # PA5-95740) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 8 min.
产品信息
PA5-95740
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 850-950 of human SON (NP_0012783401)
偶联物
形式
Liquid
浓度
1.18 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807542
产品详细信息
Positive Samples: LO2, HeLa
Immunogen sequence: TMDSQMLATS SMDSQMLASG TMDSQMLASG TMDAQMLASG TMDAQMLASS TQDSAMLGSK SPDPYRLAQD PYRLAQDPYR LGHDPYRLGH DAYRLGQDPY R
靶标信息
The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BASS1; Bax antagonist selected in Saccharomyces 1; Negative regulatory element-binding protein; NRE-binding protein; Protein DBP-5; Protein SON; SON3
基因别名: BASS1; C21orf50; DBP-5; DBP5; HSPC310; HSPC312; KIAA1019; NREBP; SON; SON3
UniProt ID: (Human) P18583
Entrez Gene ID: (Human) 6651
