Abnova

SOX18 Monoclonal Antibody (2G12)

查看其他10个SOX18抗体

产品信息

H00054345-M01A

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

2G12

抗原

SOX18 (NP_060889, 63 a.a. approximately 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

保存液

ascites

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: EPGRYGLSPA GRGERQAADE SRIRRPMNAF MVWAKDERKR LAQQNPDLHN AVLSKMLGKA WKELNAAEKR PFVEEAERLR VQHLRDHP

靶标信息

SOX18 a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: SRY (sex determining region Y)-box 18; SRY box 18; Transcription factor SOX-18

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基因别名: HLTRS; HLTS; SOX18

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UniProt ID: (Human) P35713

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Entrez Gene ID: (Human) 54345

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RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription regulatory region DNA binding protein heterodimerization activity HMG box transcription factor

negative regulation of transcription from RNA polymerase II promoter angiogenesis vasculogenesis in utero embryonic development hair follicle development vasculature development lymphangiogenesis heart looping outflow tract morphogenesis hair cycle process embryonic heart tube development mRNA transcription from RNA polymerase II promoter blood vessel endothelial cell migration negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cell maturation stem cell fate specification endocardium formation lymphatic endothelial cell differentiation endocardial cell differentiation establishment of endothelial barrier regulation of stem cell proliferation