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SOX3 Antibody (PA5-35983) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of SOX3 was performed in U-87 MG cells fixed in 4% paraformaldehyde at RT for 15 min. Green: SOX3 Polyclonal Antibody (Product # PA5-35983) diluted at 1:500. Red: beta Tubulin 3/ TUJ1 protein stained by beta Tubulin 3/ TUJ1 antibody.
产品信息
PA5-35983
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 159 of SOX3
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2553293
产品详细信息
Recommended positive controls: MCF-7.
Predicted reactivity: Mouse (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: similar to SRY (sex determining region Y)-box 3; SRY (sex determining region Y)-box 3; SRY box 3; SRY-box containing gene 3; Transcription factor SOX-3
基因别名: GHDX; MRGH; PHP; PHPX; Sox-3; SOX3; SOXB
UniProt ID: (Human) P41225
Entrez Gene ID: (Rat) 679158, (Human) 6658, (Mouse) 20675
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
central nervous system development
sensory organ development
sex determination
hypothalamus development
pituitary gland development
negative regulation of neuron differentiation
neuron development
face development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
organ morphogenesis
forebrain development
spermatid differentiation
