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Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This Protein A purified antibody is directed against human SPANX-C protein. A protein-protein BLAST analysis was used to suggest cross reactivity with most SPANX proteins from human, gorilla and chimpanzee. Reactivity against homologues from is not known.
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cancer-testis-associated protein CTp11; Cancer/testis antigen 11.3; cancer/testis antigen family 11, member 3; Cancer/testis-associated protein CTp11; cancer/testis-associated protein of 11 kD; CT11.3; Nuclear-associated protein SPAN-Xc; SPAN-Xc protein; SPANX family member C; SPANX family, member C; SPANX-C; Sperm protein associated with the nucleus on the X chromosome C; sperm protein associated with the nucleus, X chromosome, family member C
基因别名: C; CT11.3; CTp11; SPANX-C; SPANXC
UniProt ID: (Human) Q9NY87
Entrez Gene ID: (Human) 64663