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产品信息
PA5-60797
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human SPDL1. Recombinant protein control fragment (Product #RP-100098).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647825
产品详细信息
Immunogen sequence: YEPEETVEVP VLKKRREVLP VDITTAKDAC VNNSALGGEV YRLPPQKEET QSCPNSLEDN NLQLEKSVSI HTPVVSLSPH KNLPVDMQLK KEKKCVKLIG VPADA
Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 50%.
靶标信息
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Arsenite-related gene 1 protein; coiled-coil domain containing 99; Coiled-coil domain-containing protein 99; hSpindly; Protein Spindly; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; SPDL1; Spindle apparatus coiled-coil domain-containing protein 1; spindly homolog
基因别名: CCDC99; SPDL1
UniProt ID: (Human) Q96EA4
Entrez Gene ID: (Human) 54908
