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Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Spi-C transcription factor (Spi-1/PU.1 related); Transcription factor Spi-C
基因别名: SPI-C; SPIC
UniProt ID: (Human) Q8N5J4
Entrez Gene ID: (Human) 121599