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产品信息
PA5-51287
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide of human SPINK7
偶联物
形式
Liquid
浓度
1.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636734
产品详细信息
The antibody detects endogenous levels of total SPINK7 protein.
靶标信息
SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ECRG-2; esophagus cancer related gene 2; Esophagus cancer-related gene 2 protein; esophagus cancer-related gene-2; Serine protease inhibitor Kazal-type 7
基因别名: ECG2; ECRG2; SPINK7; UNQ745/PRO1474
UniProt ID: (Human) P58062
Entrez Gene ID: (Human) 84651
