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产品信息
PA5-38050
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
18 amino acid peptide near the amino terminus of human SPINSTER
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2554654
产品详细信息
A recommended positive control is human placenta tissue lysate.
At least four isoforms of SPINSTER are known to exist. This antibody is not expected to cross-react with other members of the spinster family of proteins.
靶标信息
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily. SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death. The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function.
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生物信息学
蛋白别名: HSpin1; Protein spinster homolog 1; spinster homolog 1; Spinster-like protein 1; SPNS sphingolipid transporter 1 (putative); SPNS1
基因别名: HSpin1; LAT; nrs; PP2030; PP20300; SPIN1; SPINL; SPNS1
UniProt ID: (Human) Q8TCS5
Entrez Gene ID: (Human) 83985
