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Purity is > 95% by SDS-PAGE.
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
基因别名: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; SPR
UniProt ID: (Human) P35270, (Rat) P18297
Entrez Gene ID: (Human) 6697, (Mouse) 20751, (Rat) 29270