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Product Details
PA5-87039
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human SPR.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2803793
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
Gene Aliases: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; SPR
UniProt ID: (Human) P35270, (Rat) P18297
Entrez Gene ID: (Human) 6697, (Mouse) 20751, (Rat) 29270
tetrahydrobiopterin biosynthetic process
nitric oxide biosynthetic process
regulation of nitric-oxide synthase activity
oxidation-reduction process
L-phenylalanine metabolic process
metabolic process
response to organic substance
obsolete death
pteridine metabolic process
regulation of multicellular organism growth
norepinephrine metabolic process
dopamine metabolic process
serotonin metabolic process
tetrahydrobiopterin metabolic process
cell morphogenesis involved in neuron differentiation
voluntary musculoskeletal movement
Performance Guarantee
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