Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
A300-937A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 2150 and 2200 of Human Spectrin Non-Erythroid Beta 1.
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e. g. beta-1 epsilon-1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: beta-fodrin; beta-G spectrin; Beta-II spectrin; beta-spectrin 2; beta-spectrin II; beta-spectrin non-erythrocytic 1; embryonic liver beta-fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; Fodrin beta chain; spectrin beta chain, brain 1; Spectrin beta chain, non-erythrocytic 1; spectrin, beta, non-erythrocytic 1; Spectrin, non-erythroid beta chain 1
基因别名: betaSpII; ELF; HEL102; SPTB2; SPTBN1
UniProt ID: (Human) Q01082
Entrez Gene ID: (Human) 6711
MAPK cascade
mitotic cytokinesis
ER to Golgi vesicle-mediated transport
plasma membrane organization
cytoskeleton organization
common-partner SMAD protein phosphorylation
SMAD protein import into nucleus
axon guidance
Golgi to plasma membrane protein transport
positive regulation of GTPase activity
actin filament capping
membrane assembly
protein targeting to plasma membrane
cell-cell adhesion
positive regulation of interleukin-2 secretion
regulation of protein localization to plasma membrane
positive regulation of protein localization to plasma membrane
