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产品信息
PA5-58760
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647902
产品详细信息
Immunogen sequence: PPPMNFTDLL RLAEKKQFEP VEIKVVKKSE ERPMTAEELR EREFLERKHR RKKLETDGKL PPTVSKKAPS QKESVGTK
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 79%.
靶标信息
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). Modulates RNA polymerase 1-mediated transcription. Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686I068; FLJ39441; Protein KU002155; Protein SPT2 homolog; SPT2 domain-containing protein 1; SPT2, Suppressor of Ty, domain containing 1
基因别名: Spt2; SPTY2D1
UniProt ID: (Human) Q68D10
Entrez Gene ID: (Human) 144108
