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产品信息
PA5-113785
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N terminal region of human SRD5A2 (aa 35-84).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2884300
产品详细信息
Immunogen sequence: KHTESLKPAA TRLPARAAWF LQELPSFAVP AGILARQPLS LFGPPGTVLL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 93%; Rabbit: 86%; Rat: 93%
靶标信息
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-oxo-5-alpha-steroid 4-dehydrogenase 2; 5 alpha-SR2; MGC138457; S5AR 2; SR type 2; Steroid 5-alpha-reductase 2; steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2); Type II 5-alpha reductase
基因别名: SRD5A2
UniProt ID: (Human) P31213
Entrez Gene ID: (Human) 6716
steroid biosynthetic process
androgen biosynthetic process
steroid catabolic process
cell-cell signaling
androgen metabolic process
male gonad development
biphenyl metabolic process
dibenzo-p-dioxin metabolic process
phthalate metabolic process
hippocampus development
hypothalamus development
cell differentiation
male genitalia development
female genitalia development
response to nutrient levels
response to follicle-stimulating hormone
response to testosterone
response to drug
response to peptide hormone
response to steroid hormone
oxidation-reduction process
bone development
