Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-46856
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human SRF (aa 120-169).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609485
产品详细信息
Peptide sequence: ATGGYGPVSG AVSGAKPGKK TRGRVKIKME FIDNKLRRYT TFSKRKTGIM
Sequence homology: Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. SFR is required for cardiac differentiation and maturation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: c-fos serum response element-binding transcription factor; minichromosome maintenance 1 homolog; OTTHUMP00000039820; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); SRF
基因别名: MCM1; SRF
UniProt ID: (Human) P11831
Entrez Gene ID: (Human) 6722
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
serum response element binding
chromatin DNA binding
protein homodimerization activity
histone deacetylase binding
primary miRNA binding
patterning of blood vessels
response to hypoxia
mesoderm formation
neuron migration
trophectodermal cell differentiation
heart looping
morphogenesis of an epithelial sheet
cell migration involved in sprouting angiogenesis
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription from RNA polymerase II promoter
cell-matrix adhesion
heart development
long-term memory
negative regulation of cell proliferation
associative learning
response to toxic substance
response to hormone
epithelial structure maintenance
positive regulation of transcription via serum response element binding
hippocampus development
tangential migration from the subventricular zone to the olfactory bulb
regulation of cell adhesion
platelet activation
platelet formation
negative regulation of cell migration
thyroid gland development
neuron projection development
regulation of water loss via skin
response to cytokine
megakaryocyte development
dorsal aorta morphogenesis
mRNA transcription from RNA polymerase II promoter
stress fiber assembly
skin morphogenesis
positive thymic T cell selection
sarcomere organization
positive regulation of cell differentiation
positive regulation of axon extension
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle contraction
positive regulation of transcription by glucose
muscle cell cellular homeostasis
thymus development
developmental growth
neuron development
erythrocyte development
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of smooth muscle cell differentiation
positive regulation of filopodium assembly
cardiac myofibril assembly
angiogenesis involved in wound healing
hematopoietic stem cell differentiation
positive regulation of transcription initiation from RNA polymerase II promoter
long term synaptic depression
face development
heart trabecula formation
lung morphogenesis
bronchus cartilage development
trachea cartilage development
cardiac vascular smooth muscle cell differentiation
eyelid development in camera-type eye
lung smooth muscle development
bicellular tight junction assembly
cellular response to glucose stimulus
primitive streak formation
epithelial cell-cell adhesion
cellular senescence
negative regulation of beta-amyloid clearance
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
