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This antibody is predicted to react with mouse and rat based on sequence homology.
SR proteins are a highly conserved family of arginine/serine-rich, spliceosome-associated phosphoproteins essential for metazoan pre-mRNA splicing. SR proteins act early in splicing by promoting splice site recognition and spliceosome assembly. SR proteins also play a regulatory role because they can determine alternative splice site usage in vivo and in vitro. SR proteins appear to be recruited from nuclear 'speckles', in which they are concentrated to sites of transcription in order to spatially coordinate transcription and pre-mRNA splicing within the cell nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Delayed-early protein HRS; Pre-mRNA-splicing factor SRP40; Serine/arginine-rich splicing factor 5; Splicing factor, arginine/serine-rich 5; SR splicing factor 5
基因别名: HRS; SFRS5; SRP40; SRSF5
UniProt ID: (Human) Q13243
Entrez Gene ID: (Human) 6430